Pitt Startup Check-in: Astria Biosciences

Pitt startup Astria Biosciences continues to rack up milestones as it works to bring the first simple, whole blood-based test to detect the presence and monitor the progression of cerebral aneurysms to market. It’s latest accomplishment: receiving a $275,000 SBIR Phase 1 commercialization grant from the National Science Foundation (NSF). The grant will be applied toward developing a robust data set with a focus on minorities to provide higher test fidelity in high-risk and under-represented patient groups and developing a dynamic rupture risk score that can be used to define novel aneurysm sub-groupings.

Pitt Startup Check-in: Ocugenix

Company Receives Clearance for Phase I Safety Trial for Treatment of Macular Degeneration. Alan Wells and Cecelia Yates have collaborated on and off for nearly two decades at the University of Pittsburgh developing a class of synthetic proteins that act as switches to turn off the wound healing process. Now, after nearly 7 years of pre-clinical work, the company co-founded and launched from their research has entered a Phase 1 clinical trial with its therapy for the treatment of age-related macular degeneration, also known as wet-AMD.

Pitt and UPMC Partner to Advance Promising Therapeutics Research

UPMC Enterprises Translational Sciences and the University of Pittsburgh Office of Innovation and Entrepreneurship are teaming on a second request for proposals for sponsored research projects in specific therapeutic areas. We are highlighting the two projects funded in the first RFP. We previously featured a project to develop a therapy for progressive supranuclear palsy (PSP), a debilitating neurodegenerative disease with no effective treatments. Now we feature a gene therapy from the lab of Dwi Kemaladewi, Assistant Professor of Pediatrics.

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