Innovating at the Intersection of Engineering and Medicine

The University of Pittsburgh’s Center for Medical Innovation (CMI) recently awarded grants totaling $165,000 to eight research groups through its Pilot Funding Program for Early Stage Medical Technology Research and Development.  CMI, a University Center housed in Pitt’s Swanson School of Engineering (SSOE), supports applied technology projects in the early stages of development with “kickstart” funding toward the goal of transitioning the research to clinical adoption. CMI also educates engineering students in medical product design and development through participation in real-world projects.

Grant proposals are evaluated on the basis of scientific merit, technical and clinical relevance, potential health care impact and significance, experience of the investigators, and potential in obtaining further financial investment to translate the particular solution to healthcare.

"This is our seventh year of pilot funding, and our leadership team could not be more excited with the breadth and depth of this round’s awardees,” said Alan D. Hirschman, PhD, CMI Executive Director. “This early-stage interdisciplinary research helps to develop highly specific biomedical technologies through a proven strategy of linking UPMC’s clinicians and surgeons with the Swanson School’s engineering faculty."

Since 2011, CMI has funded 67 projects, 9 of which have been spun out of Pitt as startups.

Here are the projects awarded grants in the latest rounds:

 

E-mag system for Rapid Cannulation of Fenestrated Stent Grafts to Reduce Radiation Exposure

For the development of a vascular stent graft system that will magnetically guide cannulation of endograft branches. 

Bryan W. Tillman  Division of Vascular Surgery Department of Surgery, University of Pittsburgh Medical Center
Youngjae Chun  Associate Professor, Industrial Engineering, Swanson School of Engineering 



Valved stent conduit for the treatment of severe advanced tricuspid regurgitation

For the development of an artificial tricuspid valve that will treat decreased right ventricular performance due to cardiac disease.

Catalin Toma  Assistant Professor, University of Pittsburgh School of Medicine Heart and Vascular Institute
Youngjae Chun  Associate Professor, Industrial Engineering, Swanson School of Engineering 



PopSole™ Foot Off-Loading Device

For the development of a shoe insert that will reduce foot pain due to fat pad atrophy in the feet.

Jeffrey Gusenoff  Department of Plastic Surgery, University of Pittsburgh Medical Center
Beth Gusenoff  Department of Plastic Surgery, University of Pittsburgh Medical Center
Kurt Beschorner  Associate Professor, Bioengineering, Swanson School of Engineering
Seyed Reza Moghaddam Bioengineering, Swanson School of Engineering
Steven Donahoe Bioengineering, Swanson School of Engineering



Local Induction of Tolerogenic T cells to Ameliorate Inflammation in Inflammatory Bowel Disease

For the development of a potent IBD therapy with fewer side effects than current medical therapy.

R. Warren Sands  T32 Clinical and Research Fellow, Division of Gastroenterology, Hepatology, and Nutrition
Steven R. Little  William Kepler Whiteford Endowed Professor and Chair, Department of Chemical and Petroleum Engineering
David G. Binion Professor of Medicine, Clinical and Translational Science Division of Gastroenterology, Hepatology, and Nutrition, University of Pittsburgh Medical School



MOVISU-FIT: Mobile Wearable System for Real Time Visual Feedback and Gait Training

For the development of a system to provide real-time visual feedback to patients working on gait corrections during mobility rehabilitation training.

Goeran Fiedler  Assistant Professor, Rehabilitation Science and Technology,
William Clark  Professor, Mechanical Engineering and Materials Science, Swanson School of Engineering
David Brienza  Professor, School of Health and Rehabilitation Sciences
Krista Kutina  Researcher, School of Health and Rehabilitation Sciences
Alicia Koontz  Associate Professor, Veterans Administration Hospital
April Chambers  Research Assistant Professor, Bioengineering, Swanson School of Engineering 



Polyelectrolyte Multilayer Coating for Delivery of IL-4 from Contact Lenses for Dry Eye Disease

For development of a drug-eluting contact lens for treating dry eye disease

Bryan Brown  Assistant Professor, Department of Bioengineering, McGowan Institute for Regenerative Medicine
Vishal Jhanji  Professor of Ophthalmology, UPMC Eye Center
Mangesh Kulkami  Research Assistant Professor, McGowan Institute for Regenerative Medicine



Quantitative Analysis of a New Tonometer to Manage/Prevent Glaucoma

For development of a novel pulse wave device for measurement of ocular tissue characteristics in the detection and treatment of glaucoma.

Piervincenzo Rizzo Professor, Department of Ophthalmology
Ian Sigal  Assistant Professor, Department of Ophthalmology
Ian Conner  Assistant Professor of Ophthalmology



Acetone Breathalyzer for Monitoring the Ketogenic State

For development of a cost-effective rapid acetone breath-alyzer for clinical and consumer usage in ketogenic diets

Sung Kwon Cho  Professor, Department of Mechanical Engineering and Materials Science
David Rometo  Assistant Professor, Division of Endocrinology and Metabolism
David Finegold  Professor, Department of Human Genetics
Alex Star  Professor, Department of Chemistry

If you are a Pitt researcher that would like to submit a CMI grant application, click here.

If you are interested in learning more about any of these projects, including sponsored research and licensing, contact the Innovation Institute at innovate@pitt.edu.

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